Bone Cell and Tissue Mechanics
Invited Lecturers
- Stephen C. Cowin (City University of New York, USA)
1. Bone structure and microstructure.
2. Introduction of participants & lecturers.
3. The mechanosensory system in bone.
4. Russian doll poroelasticity.
5. Diagnostic bone ultrasound.
6. Friday Q&A- John Currey (University of York, Great Britain)
1. Form-mechanical property relationships in whole bones.
2. Composition-mechanical property relationships in bone tissue.
3. Histology-mechanical property relationships in bone tissue.
4. The role of microdamage in bone mechanics.
5. Recent developments in testing bone tissue and whole bone mechanical behaviour.
6. Monday Q&A- Manuel Doblaré (University of Zaragoza, Spain)
1. Introduction to the macroscopic mechanical behavior of bone tissue; computational models for the prediction of bone fracture.
2. Damage-based phenomenological models of bone remodeling.
3. Mechanistic models of bone remodeling.
4. Computational simulation of bone fracture healing.
5. Computational simulation of bone osseointegration.
6. Thursday Q&A- Alicia J. El Haj (Keele University Medical School, Stoke-on-Trent, Great Britain)
1. Bone cell biology.
2. Differentiation of bone cells and the bone cell lineage.
3. Bone development and remodelling.
4. Mechanotransduction and bone cell signalling.
5. Controlling bone cells by physical forces/Applied cell biomechanics.
6. Bone cell apoptosis and cell turnover.
7. Tuesday Q&A- Allen E. Goodship (UCL, Stanmore, Great Britain)
1. Bone modeling and remodeling.
2. Functional adaptation in bone – part one.
3. Functional adaptation in bone – part two.
4. Fracture repair in bone.
5. Mechanically related modulation of bone repair.
6. Mechanogenetics of bone – potential implications for mechanical competence, repair and replacement of the skeleton.
7. Wednesday Q&A- Gastone Marotti (Università di Modena e Reggio Emilia, Modena, Italy)
1. Quantitative data on bone formation rate throughout the skeletal system.
2. The structure of bone tissues.
3. The mechanism of transduction of mechanical strains into biological signals at the bone cellular level.